Isoglutamine tert-butyl ester hydrochloride - Names and Identifiers
Isoglutamine tert-butyl ester hydrochloride - Physico-chemical Properties
Molecular Formula | C9H19ClN2O3
|
Molar Mass | 238.71 |
Solubility | DMSO (Slightly), Methanol (Slightly, Sonicated), Water (Slightly) |
Storage Condition | Inert atmosphere,2-8°C |
Stability | Hygroscopic |
Isoglutamine tert-butyl ester hydrochloride - Introduction
H-Glu(OtBu)-NH2.HCl (H-Glu(OtBu)-NH2.HCl) is an organic compound which is obtained by reacting tert-butyl (S)-4,5-diamino-5-oxopentanoate with hydrochloric acid. The following is a detailed description of its nature, use, formulation and safety information:
Nature:
-Appearance: White crystalline powder
-Molecular formula: C11H22ClNO4
-Molecular weight: 267.75g/mol
-Melting point: 143-144°C
Use:
H-Glu(OtBu)-NH2.HCl has a variety of applications in chemical research and synthesis, including:
-Used as a synthetic intermediate in the pharmaceutical field and can be used to synthesize biologically active molecules.
-Used as a protecting group for proteins or peptides to enhance their stability and solubility.
-Used to synthesize peptide chains of specific sequences in peptide synthesis and chemical biology research.
Preparation Method:
The preparation of H-Glu(OtBu)-NH2. HCl is usually completed by the following steps:
1. reacting tert-butyl (S)-4,5-diamino-5-oxopentanoate with hydrochloric acid to generate tert-butyl (S)-4,5-diamino-5-oxopentanoate hydrochloride.
2. The produced tert-butyl (S)-4,5-diamino-5-oxopentanoate hydrochloride is crystallized from an appropriate solvent to give H-Glu(OtBu)-NH2.HCl.
Safety Information:
H-Glu(OtBu)-NH2.HCl is generally considered to be relatively safe when used under appropriate operating conditions. But still need to pay attention to the following matters:
-It may be irritating to eyes and skin, please avoid contact.
-During handling and operation, please wear appropriate personal protective equipment, such as laboratory gloves and safety glasses.
-Please store and handle the compound properly to avoid accidents.
-Observe appropriate laboratory safety procedures and guidelines when using and disposing of the compound.
Please note that chemical experiments and applications may have certain risks. It is recommended to use and handle chemical substances under professional guidance.
Last Update:2024-04-09 19:05:53